In the latest research report compiled by Global Market Insights Inc., polyglycerol sebacate (PGS) market size has been projected to grow substantially by 2025.

Of late, development in polyglycerol sebacate market has been gaining prominence in a slew of biomaterial applications. The robustly degradable and elastomeric polymer is being highly sought-after in a range of applications in drug delivery and soft tissue engineering.

It is worth noting that PGS polymer is profoundly being produced from low cost and non-toxic monomers and exhibits tunable elastomeric mechanical attributes and degradation under physiological conditions.

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Industry dynamics and trends which can redefine the business outlook are delineated below:

Trends in tissue engineering

Traction for polyglycerol sebacate (PGS) market in tissue engineering application has increased in the wake of its biocompability and elastomeric mechanical properties. FDA approval of sebacic acid copolymers meant for drug delivery matrices has further instilled confidence of stakeholders.

Research and development activities toward the application of PGS in tissue engineering for drug delivery, cardiac patches, tympanic perforations, retinal transplantation, microfluids and neural repair will have an impact on the market.

PGS materials have become highly desirable in the light of its flexible, robust, and soft attributes and low cost. Tissue engineering is likely to be the driving force of innovation as PGS-based medical applications is slated to boost the market share.

Growth drivers: Drug delivery application portfolio

Leading companies are infusing investment in polyglycerol sebacate market for drug delivery application in a bid to withstand the therapeutic effects of drugs. Notably, drug delivery has become popular as having a slew of applications, including infection disease, anticancer therapy and contraceptive methods.

Use of PGS for tissue adhesives will further boost the confidence of stakeholders on the heels of soaring demand in the clinic for biodegradable polymer adhesives which can cover the mechanical deformations. Moreover, dipping popularity of conventional staples and sutures owing to presence of toxicity and lack of elastic behavior has triggered growth in PGS space.

Opportunities in coating application

Inclination for PGS in biomedical space is offering a myriad of upsides given that its biocompatible and elastic nature has become the linchpin for researchers and other stakeholders.

Stakeholders may find opportunities galore in coating application as it is being formulated as a coating for a slew of medical implants, rods, and sheets. Besides, PGS’s compatibility with a slew of biologic materials such as bone minerals, collagen has made it highly sought-after among end-markets.

Investment in North America is likely to fare well for the producers of PGS given the developed countries such as the U.S. have been witnessed increased demand in drug delivery and coating. Prominently, advent of smart implants is also expected to boost the PGS business outlook.

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Challenges: Solubility

While polyglycerol sebacate market will continue to gain grounds, some of the downsides linked with processability and solubility may derail PGS market growth. Besides, easy availability of substitute products may not go well with the industry size expansion.

Growing traction for tissue engineering globally will become more pronounced in the next five years. With increased prominence of soft gel, drug delivery, and coating in North America, Europe and APAC, infusing of funds in PCG market is likely to surge through 2025.

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